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Let us turn your assignments into the highest grades! A young boy coughing due to pertussis. This is then followed by weeks of severe coughing fits. Following a fit of coughing, a high-pitched whoop sound or gasp may occur as the person breathes in.
The coughing may last for 10 or more weeks, hence the phrase “100-day cough”. The time between infection and the onset of symptoms is usually seven to ten days. Disease may occur in those who have been vaccinated, but symptoms are typically milder. People are infectious to others from the start of symptoms until about three weeks into the coughing fits. Initial immunization is recommended between six and eight weeks of age, with four doses to be given in the first two years of life. The vaccine becomes less effective over time, with additional doses often recommended for older children and adults.
Antibiotics may be used to prevent the disease in those who have been exposed and are at risk of severe disease. In those with the disease, antibiotics are useful if started within three weeks of the initial symptoms, but otherwise have little effect in most people. In children less than one year old and among those who are pregnant, they are recommended within six weeks of symptom onset. Evidence to support interventions, other than antibiotics, for the cough is poor. Many children less than a year of age require hospitalization. 3 million people worldwide were infected in 2015. Outbreaks of the disease were first described in the 16th century.
The bacterium that causes the infection was discovered in 1906. The pertussis vaccine became available in the 1940s. Vomiting after a coughing spell or an inspiratory whooping sound on coughing, almost doubles the likelihood that the illness is pertussis. This stage usually lasts two to eight weeks, or sometimes longer. A gradual transition then occurs to the convalescent stage, which usually lasts one to four weeks. This stage is marked by a decrease in paroxysms of coughing, both in frequency and severity, and a cessation of vomiting.